The modern era for Chateau Chasse Spleen starts in 1976 when the estate was bought by the Merlaut family. At the time of the purchase, Chasse Spleen owned about 40 hectares of vines. Under the direction of Jacques Merlaut and his daughter, Bernadotte Villars they expanded their vineyard holdings so that today, Chasse Spleen has 80 hectares of vines. They replanted large sections of the vineyard to increase the vine density. They also updated and modernized their wine making facilities.

Château Chasse-Spleen is a winery in the Moulis-en-Médoc appellation to the west of Margaux. It has long been viewed as the leading estate in that appellation – alongside Château Poujeaux – and is widely regarded, if not of being at cru classé standard, then certainly as holding a place among the top wines just beneath the classification. It was selected as one of six Crus Exceptionnels in the Cru Bourgeois classification in 1932 and maintained that status until the annulment of the classification in 2007. The wines are prized for their well-balanced fruitiness across a range of vintages. A second wine, L’Heritage de Chasse-Spleen, was known as L’Ermitage before 2000. L’Oratoire de Chasse-Spleen is the third wine. A white wine is also made, featuring around two-thirds Semillon to one-third Sauvignon Blanc.